Eligard Depot 45mg injection consists of the active ingredient Leuprolide acetate. It belongs to the class of medicines called gonadotropin-releasing hormone (GnRH) agonists. This injection treats prostate cancer in men, hormone-responsive breast cancer, endometriosis (tissue that usually lines the interior of the uterus grows outside of it), and uterine fibroids (noncancerous growths of the uterus) in women. This medicine is also used for the treatment of premature puberty, which is characterized by early physical development in children due to hormonal imbalances.